Treatment tools

Below are statistical treatment tools developed at Cedars-Sinai for breast cancer treatment.

Treatment tools for breast cancer

Resource

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Description

Treatment Discontinuation Risk

The Biostatistics Department has also developed a novel web application to estimate the risk of treatment discontinuation of breast cancer patients undergoing treatment with anastrozole or tamoxifen. The application is based on a dynamic risk prediction model where the clinician inputs a patient’s baseline body mass index (BMI), selected PRO symptoms collected over time up to 6 or 12 months, and requests the probability that the patient will stop treatment by a pre-specified time in the future.

Link to anastrozole and Link to tamoxifen

Treatment Tolerability

This resource has been published by the Biostatistics department of Cedars-Sinai Medical Center. Visualization tools were developed to explore and visualize clinical trial tolerability data for patients, clinicians, and researchers. Specifically, a novel interactive web application was developed using R and the Shiny web application framework to display numerical and graphical summary statistics of treatment tolerability and QOL over time in cancer patients. The application has four facing tools: Adverse event (AE) explorer, QOL cohort explorer, AE cohort explorer, and AE/QOL explorer.

Link to resource